Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
A. Signalling pathways involved in palatal epithelial differentiation include Fgf10, Irf6, and Tbx1 pathways. Mutations of genes involved in these pathways can lead to clefting. B. Signalling cascade involved in loss of the medial edge epithelium. (From Lane J, Kaartinen V. Signaling networks in palate development. Wiley Interdiscip Rev Syst Biol Med 2014;6:13.)
