Table 1.

Cytokine levels (pg/mL) in terminal blood serum collected from naïve, Non-Dep and Dep mice.

pg/ml	Naïve	Non-Dependent	Dependent
IL-1α	380.4 ± 44.39	406.3 ± 46.43	224.2 ± 26.74*,##
IL-1β	3.39 ± 0.62	1.94 ± 0.41	4.79 ± 2.61
G-CSF	583.7 ± 204.7	581.4 ± 294.2	310.5 ± 76.4
Eotaxin	577.7 ± 41.8	451.4 ± 33.0*	381.2 ± 28.1**
GM-CSF	4.03 ± 1.2	0.7 ± 0.5	7.1 ± 4.1
IFNγ	0.08 ± 0.05	0.02 ± 0.02	0.8 ± 0.5
IL-2	0.72 ± 0.4	0.01 ± 0.01	n.d.
IL-3	0.36 ± 0.2	0.007 ± 0.007	0.52 ± 0.5
IL-4	0.98 ± 0.03	0.86 ± 0.01*	0.80 ± 0.03***
IL-5	3.03 ± 0.43	2.48 ± 0.70	25.58 ± 17.67
IL-6	17.8 ± 8.0	24.2 ± 13.5	9.66 ± 2.82
IL-7	2.92 ± 2.47	7.02 ± 6.54	0.65 ± 0.63
IL-9	150.3 ± 26.0	197.8 ± 48.8	121.1 ± 14.3
IL-10	2.01 ± 0.38	0.97 ± 0.20*	0.61 ± 0.25**
IL-12 (p40)	9.48 ± 3.98	2.45 ± 0.58	5.55 ± 4.32***
IL-12 (p70)	3.53 ± 1.06	0.08 ± 0.08**	1.29 ± 0.93**
LIF	0.93 ± 0.21	0.93 ± 0.13###	0.45 ± 0.11**
IL-13	37.9 ± 5.01	31.0 ± 3.09	23.5 ± 2.47*
LIX	4369 ± 351.6	4663 ± 245.2	3271 ± 273.6*,##
IL-15	59.05 ± 4.63	51.6 ± 6.00	19.8 ± 6.35***,###
IL-17	0.91 ± 0.21	0.02 ± 0.01***	0.38 ± 0.19**
IP-10	126.1 ± 11.0	103.6 ± 8.17	258.1 ± 45.0#
KC	145.9 ± 51.6	225.4 ± 85.4	88.1 ± 25.1
MCP1	19.2 ± 8.90	11.7 ± 5.1	13.2 ± 5.27
MIP-1a	40.3 ± 3.33	29.2 ± 3.92	13.8 ± 3.56***,#
MIP-1b	19.5 ± 2.63	14.5 ± 2.26	26.1 ± 4.53
M-CSF	111.9 ± 80.5	208.5 ± 102.8	289.3 ± 115.7
MIP-2	111.9 ± 11.6	78.3 ± 4.03	50.5 ± 12.6***,#
MIG	39.0 ± 3.28	45.2 ± 5.29	107.9 ± 28.1
RANTES	20.1 ± 2.28	16.7 ± 2.78	11.4 ± 2.13*
VGF	2.46 ± 0.32	2.796 ± 0.46	2.28 ± 0.33
TNFα	0.41 ± 0.20	0.11 ± 0.07	1.71 ± 1.10

^*p < 0.05

^**p < 0.01

^***p < 0.001 compared to Naïve

^#p < 0.05

^##p < 0.01

^###p < 0.001 for Non-Dep versus Dep by one-way ANOVA and Tukey posthoc test; n = 17 – 22 mice.