Fig. 1.

Pancreatic acinar cell-specific expression of cyclooxygenase (COX)-2. A: schema of transgenic expression of COX-2 in mouse pancreatic acinar cells. B: Western blot showed COX-2 was expressed in COX-2/Cre mice, but not Cre mice. COX-1 expression was not affected (20 wk). C: pancreas, stomach, lung, and intestine were harvested from wild-type mice, and Western blot analysis was performed using COX-1 and COX-2 antibodies. Note: anti-COX-1 is a mouse monoclonal antibody. Some immunoglobulin-rich tissues showed strong nonspecific bands from secondary anti-mouse antibody.