Effects of prolonged intake of desloratadine on lymphatic tone and lymphatic diastolic resistance of mesenteric lymphatic vessels before (A and B, at range of transmural pressures 1, 3, and 5 cmH2O) and after (C and D, at transmural pressure 5 cmH2O) elimination of the effects of histamine and nitric oxide. group C, control group; group D, desloratadine-treated group. α-HMD, α-methyl-dl-histidine dihydrochloride; l-NAME, Nω-nitro-l-arginine methyl ester hydrochloride. *Significant differences (P < 0.05) between group C and group D under similar conditions; #significant differences (P < 0.05) between control conditions and any treatment condition within each experimental group; n = 6 for each group.