Table 1.
5-HT and norepinephrine levels in the spinal cord of control and 5,7-DHT WT and SERT-KO rats
5-HT Levels (n) |
Norepinephrine Levels (n) |
|||
---|---|---|---|---|
Control | 5,7-DHT treated | Control | 5,7-DHT treated | |
WT male | 279 ± 33 (5) | 140 ± 40 (4)* | 133 ± 41 (2) | 132 ± 11 (3) |
SERT-KO male | 161 ± 34 (5) | 87 ± 7 (5) | 158 + 39 (2) | 101 ± 9 (3) |
WT female | 224 ± 38 (5) | 72 ± 18 (5)* | 121 ± 24 (2) | 144 + 30 (5) |
SERT-KO female | 178 ± 10 (7) | 122 ± 9 (6)* | 190 ± 13 (3) | 182 ± 25 (5) |
Values are means ± SE. 5,7-DHT, 5,7-dihydroxytryptamine; 5-HT, 5-hydroxytryptamine; SERT-KO, serotonin transporter-knockout; WT, wild type.
Significantly different from control rats.