Table 4.
KEGG pathway analysis of target genes associated with IIA stage colon cancer.
| Regulated | Category | Term | Count | % | P-Value | Fold Enrichment | FDR |
|---|---|---|---|---|---|---|---|
| Up | KEGG_PATHWAY | hsa04360:Axon guidance | 21 | 2.24 | 7.30E-06 | 3.173885 | 0.009462 |
| Up | KEGG_PATHWAY | hsa04010:MAPK signaling pathway | 31 | 3.30 | 1.94E-05 | 2.333442 | 0.025073 |
| Up | KEGG_PATHWAY | hsa04144:Endocytosis | 31 | 3.30 | 2.43E-05 | 2.306309 | 0.031476 |
| Up | KEGG_PATHWAY | hsa05205:Proteoglycans in cancer | 26 | 2.77 | 3.53E-05 | 2.495278 | 0.045696 |
| Up | KEGG_PATHWAY | hsa04068:FoxO signaling pathway | 20 | 2.13 | 5.61E-05 | 2.864842 | 0.072721 |
| Down | KEGG_PATHWAY | hsa05200:Pathways in cancer | 108 | 3.73 | 1.58E-10 | 1.810230026 | 2.10E-07 |
| Down | KEGG_PATHWAY | hsa04510:Focal adhesion | 66 | 2.28 | 1.44E-09 | 2.110470443 | 1.90E-06 |
| Down | KEGG_PATHWAY | hsa04151:PI3K-Akt signaling pathway | 91 | 3.14 | 4.76E-08 | 1.737500173 | 6.31E-05 |
| Down | KEGG_PATHWAY | hsa05222:Small cell lung cancer | 32 | 1.11 | 9.87E-07 | 2.479896821 | 0.001306893 |
| Down | KEGG_PATHWAY | hsa04550:Signaling pathways regulating pluripotency of stem cells | 44 | 1.52 | 2.04E-06 | 2.070271006 | 0.002694908 |