Figure 5.

Simvastatin inhibits the nuclear translocation of NF-κB in heart tissue of diabetic rats. Representative photographs of Western blot of protein expression in nucleus (upper panel) and the quantification (lower panel). (A) p65 in nucleus. (B) p65 in cytoplasm. (C) IκBα in cytoplasm. (D) Representative images for the histochemical staining for p65 accumulation in the formalin-fixed heart tissues (400× magnification). Data are expressed as the mean ±SD. n=4. * p<0.05 was considered statistically significant.