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. 2019 Feb 15;25:1220–1231. doi: 10.12659/MSM.911714

Figure 4.

Figure 4

(A, B) Effects of resveratrol and PGC1α siRNA on HG-induced protein expression of SIRT1, PGC1α, NRF1, and TFAM in podocytes. Podocytes were incubated with normal glucose (5.6 mM, NG), high glucose (30 mM, HG), high glucose +PGC1 siRNA (HG+PGC1 siRNA), high glucose+resveratrol (10 μmol/L, HG+Res), and high glucose +PGC1 siRNA+resveratrol (HG+PGC1 siRNA+Res) for 48 h. The relative intensities were normalized against β-actin. The values are expressed as mean ±SD. * P<0.05, **P<0.01 vs. high glucose group; ## P<0.01 vs. high glucose + resveratrol group.