Figure 4.

Suppression of POU5F1B promoted G1 cell cycle arrest and increased apoptosis of cervical cancer cells in vitro. (A) Flow cytometry was used to detect the cell cycle regulation. The bar chart represents the percentage of cancer cells in G0/G1, S, or G2/M phase of the cell cycle. (B) The apoptosis rate of cells determined by flow cytometry analysis. (C) The apoptosis of cells was detected by Hoechst 33258 staining. * P<0.05, ** P<0.01, *** P<0.001. Results represent the mean ±SD of triplicate wells in three independent experiments.