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A: representative microphotographs of the muscularized arteries of rats treated with plain drugs and formulations. B and C: effect of the drugs or formulations on arterial medial wall thickening (B) and extent of muscularized pulmonary arteries (C). IT, intratracheal; MP, microparticles; Ros, rosiglitazone; Sil, sildenafil. Data were analyzed using one-way ANOVA followed by Fisher’s least significant difference test; n = 3–4, *P < 0.05.
