Shared and unique transcriptional responses between male and female acid-challenged piglets. Venn diagram demonstrates unique and shared transcripts that increased or decreased in the epithelial transcriptome of male and female piglets (A), in the nodose ganglia transcriptome of male and female piglets (B), and in the brain stem of male and female piglets (C). Venn diagram demonstrates unique and shared biological pathways from overrepresented transcripts that increased or decreased in the epithelia of male and female piglets (D) in the nodose ganglia of male and female piglets (E), and in the brain stem of male and female piglets (G). For all panels, n = 3 piglets each group. M, male; F, female.