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Schematic diagram of CICT. (A) Skin cells were collected from a donor cow and cultured in vitro. (B) Matured oocytes were enucleated. (C) The donor cell and oocyte cytoplasm (green) were injected into the enucleated recipient oocyte (orange). (D) The reconstructed oocytes were fused, and presumed cloned embryos were allowed to develop to the blastocyst stage in vitro. CICT, cytoplasm injection cloning technology. Color images available online.
