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. 2019 Feb 19;34(1):692–702. doi: 10.1080/14756366.2019.1577831

Figure 1.

Figure 1.

Matriptase could differentially be regulated between haematological and epithelial/carcinoma cells. (A) The mRNA expression levels for matriptase, HAI-1, and HAI-2 in a variety of cell lines were obtained from the CCLE databases. An RNA-seq reading count lower than 10 RPKM (Reads Per Kilobase Million) was identified as absent transcript expression. The number of cell lines expressing the three proteins and the number of the cell lines with overlapping expression of the three proteins are presented with their distribution within the circles. (B) The cell lines collected in the CCLE database were grouped into epithelial (carcinoma) and haematological (lymphoid and haematopoietic neoplasm) based on their cell-type origin. Chi-square testing was applied to compare differences between the ratio of matriptase with HAI-1, HAI-2 alone or no HAIs in epithelial origin and haematological origin. ****p < .001. (C) The ratio of matriptase to HAIs, HAI-1 alone, HAI-2 alone, or lack of HAIs co-expression was presented in the Pie chart of the epithelial origin or haematological origin, respectively.