Table 1.
Applications of pH-sensitive liposomes for anticancer drug delivery.
| Liposome | Encapsulated drug | Therapeutic applications | Reference |
|---|---|---|---|
| MGlu-Dex-modified liposomes | Ovalbumin (OVA) | E.G7-OVA tumor | [70] |
| ECM-targeting liposomes | DOX-HCl | HCT116 cells | [69] |
| POPC/DSPE-PG8MG liposomes | Geranylgeranyltransferase-I inhibitor (GGTI) | Human breast cancer cell line of MCF-7, pancreatic cancer cell line of MiaPaCa2 | [72] |
| MGluPG-modified liposomes | OVA and IFN-γ-encoding plasmid DNA (pDNA) | E.G7-OVA tumor | [73] |
| DC-Chol/DOPE liposomes pH-sensitive PEGylated liposomes | pDNA | Human hepatocellular carcinoma (HepG2) | [74] |
| DOPE/OA/Chol/DSPE–PEG–MAL [anti-CD3] | pEGlacZ b-Gal condensed with poly-l-lysine | Transfection of Jurkat T-leukemia cells | [75] |
| DOPE/HSPC/CHEMS/CHOL/mPEG2000-DSPEDOPE/HSPC/CHEMS/CHOL | DOX | Cancer therapy (B lymphoma cells) | [76] |