Capsaicin (Cap) does not modulate the overall inhibitory neurotransmission of TRPV1Cre/tdTom neurons. A: representative recording of miniature inhibitory postsynaptic currents (mIPSCs) from a transient receptor potential vanilloid type 1 (TRPV1)-expressing dorsomedial hypothalamic nucleus (DMH) neuron. TTX, tetrodotoxin. B: Cap had no significant effect on the baseline (B1), overall frequency (B3), and amplitude (B4) of mIPSCs in TRPV1Cre/tdTom DMH neurons. C: representative recording of mIPSCs from a TRPV1-expressing paraventricular nucleus of the hypothalamus (PVN) neuron. D: Cap had no significant effect on the baseline (D1), overall frequency (D3), and amplitude (D4) of mIPSCs in TRPV1Cre/tdTom PVN neurons. Numbers in B2 and D2 indicate number of neurons.