Table 1.

Dopamine and metabolite changes in various brain regions of mice following exposure to 765 ppm of H₂S

				H2S
			Breathing air	Day 1	Day 3	Day 7
Inferior colliculus	Dopamine
		Male	100.0 ± 3.33	162.4 ± 20.29**	146.3 ± 9.87**	173.5 ± 26.45*
		Female	100.0 ± 7.13	195.3 ± 23.00*	166 ± 15.97**	164 ± 11.99**
	DOPAC
		Male	100.0 ± 7.41	272.6 ± 44.19**	148.9 ± 9.56*	186.3 ± 32.42*
		Female	100.0 ± 3.31	210.3 ± 25.85*	135 ± 20.43**	157.4 ± 11.75**
	HVA
		Male	100.0 ± 3.26	129.1 ± 7.04**	139.1 ± 8.14**	150 ± 20.53*
		Female	100.0 ± 13.05	155.1 ± 12.59*	74.07 ± 25.58	112.5 ± 8.82
Thalamus	Dopamine
		Male	100.0 ± 31.89	214.7 ± 89.37	75.39 ± 58.87	138.5 ± 62.97
		Female	100.0 ± 16.82	80.58 ± 15.67	62.35 ± 6.99	51.86 ± 20.70
	DOPAC
		Male	100.0 ± 16.82	80.58 ± 15.67	62.35 ± 6.99	51.86 ± 20.70
		Female	100.00 ± 20.42	103.5 ± 15.74	38.57 ± 2.26	56.81 ± 18.02
	HVA
		Male	100.0 ± 20.99	180.3 ± 26.67	79.74 ± 48.29	218.7 ± 49.09
		Female	100.0 ± 14.33	77.47 ± 13.55	64.54 ± 7.55	65.33 ± 24.21
Cortex	Dopamine
		Male	100.00 ± 19.07	192.9 ± 75.87	241.9 ± 35.64**	191.1 ± 42.53
		Female	100.0 ± 9.05	127.1 ± 21.2	159.9 ± 41.83	104.6 ± 7.36
	DOPAC
		Male	95.6 ± 14.73	99.94 ± 32.47	217.2 ± 34.50*	126.8 ± 9.04
		Female	95.6 ± 8.54	118.7 ± 18.99	186.9 ± 43.53	108 ± 7.35
	HVA
		Male	95.6 ± 10.97	116.1 ± 32.05	230.4 ± 30.91**	128.5 ± 11.12
		Female	95.6 ± 8.58	113.3 ± 17.8	186.6 ± 42.63	114.1 ± 11.4
Striatum	Dopamine
		Male	95.6 ± 11.84	171 ± 28.32**	163.6 ± 52.26	104.2 ± 18.66
		Female	100.0 ± 17.74	187.2 ± 44.11	100.1 ± 8.93	83.67 ± 6.43
	DOPAC
		Male	100.0 ± 10.5	131.9 ± 15.84	132 ± 10.79	152.7 ± 34.4
		Female	100.0 ± 19.77	59.1 ± 41.65	15.17 ± 13.52**	2.16 ± 0.52**
	HVA
		Male	100.0 ± 8.19	142.8 ± 22.03	125.1 ± 6.84	131.2 ± 20.09
		Female	100 ± 21.92	166.3 ± 36.74	97.2 ± 7.49	94.36 ± 6.11

Note: n = 4–5/group.

^*,P < 0.05;

^**,P < 0.01 compared with breathing-air controls.