B) Classified according to antibodies (n = 55).

	Anti-EGFR (n = 17)		Anti-VEGF (n = 38)
	Any grade, n (%)	Grade 3/4, n (%)	Any grade, n (%)	Grade 3/4, n (%)	P value
Leukopenia	14 (82)	1 (6)	30 (79)	2 (5)	1.00
Neutropenia	15 (88)	9 (53)	29 (76)	19 (50)	0.830
Anemia	6 (35)	0	24 (63)	0	0.318
Thrombocytopenia	6 (35)	0	8 (21)	0	0.527
Hypomagnesemia	10 (59)	2 (12)	6 (16)	0	0.039
Alopecia	4 (24)	0	2 (6)	0	0.169
Fatigue	6 (35)	0	16 (43)	0	1.00
FN	0	0	0	0	–
Diarrhea	13 (77)	2 (12)	18 (49)	1 (3)	0.350
Anorexia	8 (47)	0	9 (24)	0	0.253
Nausea	12 (70)	1 (6)	17 (46)	0	0.347
Neurotoxicity	13 (77)	0	30 (81)	1 (3)	1.00
Hypertension	2 (12)	0	21 (57)	0	0.045
Proteinuria	5 (29)	0	22 (60)	1 (3)	0.295
Rash acneiform	15 (88)	0	3 (8)	0	<0.001