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. Author manuscript; available in PMC: 2019 Feb 21.
Published in final edited form as: Mult Scler. 2016 Dec 7;23(11):1469–1478. doi: 10.1177/1352458516681504

Figure 3.

Figure 3

Correlations of neurodegeneration measures with [11C]PBR28 distribution volume ratio (DVR). (a) The normalised concentration of N-acetyl aspartate (NAA) was negatively correlated with the average DVR in T2 FLAIR white matter lesions (Spearman’s ρ = –0.443, p = 0.034). (b) The whole brain normalised grey matter volume was correlated with DVR of white matter lesions within the spectroscopy volume weighted by the white matter lesion tissue fraction (ρ = –0.535, p = 0.009). The dashed line is the regression line and black dots describe data from different patients (n = 23).