Table 1.
Clinical and demographical data of individual patients included in analysis
| Participant | MRI data | ICD-10 diagnosis | Age, years | Gender | HRSD baseline | HRSD post-ECT | ECT sessions | Mean seizure duration, s | Maximum stimulus, % | Continued psychopharmacological medication | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Antidepressants | Augmentation | Sedatives/anxiolytics | ||||||||||
| 1 | Post-ECT MRI missing | F33.3 | 47 | Woman | 25 | 10 | 8 | 24.9 | 100 | duloxetine 120 mg trazodone 300 mg |
aripiprazole 30 mg risperidone 2 mg | lorazepam 5 mg levomepromazine 25 mg |
| 2 | 2nd baseline MRI missing | F33.2 | 50 | Woman | 24 | 5 | 8 | 32.0 | 100 | venlafaxine 300 mg amitriptyline 100 mg | aripiprazole 20 mg | prothipendyl 80 mg |
| 3 | Complete | F33.2 | 40 | Man | 23 | 11 | 8 | 59.4 | 80 | venlafaxine 300 mg mirtazapine 60 mg | quetiapine 75 mg | clonazepam 1.5 mg |
| 4 | Complete | F33.2 | 55 | Woman | 23 | 7 | 8 | 56.3 | 50 | vortioxetine 40 mg | quetiapine 300 mg lamotrigine 50 mg | clonazepam 0.5 mg |
| 5 | Complete | F33.3 | 43 | Woman | 28 | 10 | 8 | 38.3 | 100 | venlafaxine 225 mg trazodone 150 mg | quetiapine 400 mg risperidone 4 mg | – |
| 6 | Complete | F33.2 | 42 | Man | 23 | 16 | 10 | 33.9 | 200 | escitalopram 20 mg | lamotrigine 200 mg | – |
| 7 | Complete | F33.2 | 56 | Woman | 23 | 1 | 10 | 38.4 | 150 | vortioxetine 10 mg escitalopram 30 mg venlafaxine 225 mg | lamotrigine 100 mg | lorazepam 3 mg |
| 8 | Subcortical data in post-ECT MRI excluded | F33.2 | 53 | Woman | 33 | 4 | 9 | 26.7 | 150 | fluoxetine 40 mg mianserin 60 mg | – | clonazepam 2 mg pregabalin 250 mg prothipendyl 80 mg |
| 9 | Complete | F32.2 | 41 | Woman | 31 | 5 | 8 | 31.9 | 100 | sertraline 150 mg trazodone 150 mg | risperidone 0.5 mg | clonazepam 1 mg |
| 10 | Complete | F33.2 | 33 | Woman | 22 | 5 | 8 | 44.6 | 40 | sertraline 150 mg | aripiprazole 5 mg | lorazepam 1.5 mg |
| 11 | Complete | F33.2 | 49 | Woman | 23 | 7 | 11 | 43.1 | 100 | vortioxetine 20 mg trazodone 50 mg | aripiprazole 5 mg | clonazepam 0.25 mg |
| 12 | Complete | F33.2 | 35 | Man | 24 | 12 | 8 | 55.5 | 50 | escitalopram 20 mg | quetiapine 50 mg | – |
| 13 | 2nd baseline MRI missing | F33.2 | 58 | Woman | 27 | 3 | 8 | 49.9 | 100 | venlafaxine 300 mg mirtazapine 30 mg | aripiprazole 5 mg quetiapine 50 mg | lorazepam 2.5 mg |
| 14 | Subcortical data in 2nd baseline MRI excluded | F33.3 | 55 | Woman | 26 | 3 | 8 | 44.4 | 50 | sertraline 150 mg, mirtazapine 45 mg | aripiprazole 15 mg | lorazepam 5 mg |
MRI, magnetic resonance imaging; HRSD, Hamilton Rating Scale for Depression; ECT, electroconvulsive therapy.