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. 2019 Feb 5;10(11):1171–1192. doi: 10.18632/oncotarget.26622

Figure 2. Effects of FGF2 knockdown in pemetrexed-resistant lung cancer cells.

Figure 2

The expression of FGF2 in PC9-MTA and H1993-MTA cells was inhibited by siRNA, and the sensitivity to pemetrexed was tested using WST assays. (A) Sensitivity to pemetrexed was measured in PC9-MTA cells transfected with siRNA targeting control (si-control) or FGF2 (si-FGF2) and the parental PC9 cells (P). (B) Sensitivity to pemetrexed was measured in H1993-MTA cells transfected with siRNA (si-control or si-FGF2) and the parental H1993 cells (P). The error bars in each graph represent the standard error of the value obtained in the experiments performed in triplicate. (C) FGF2 expression as determined by the Western blot analyses in PC9-MTA cells and H1993-MTA cells transfected with si-FGF2 or si-control.