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. 2019 Feb 5;10(11):1171–1192. doi: 10.18632/oncotarget.26622

Figure 6. Effects of individual or dual knockdown of FGF2 and TS on sensitivity to pemetrexed in the pemetrexed-resistant lung cancer cells.

Figure 6

(A) FGF2 and TS expression as determined by Western blot analyses in the PC9-MTA cells and H1993-MTA cells transfected with control siRNA (si-control), siRNA targeting FGF2 (si-FGF2), siRNA targeting TS (si-TS), or both (si-FGF2 + TS). β-actin was used as a loading control. (B, C) Sensitivity to pemetrexed was measured in PC9-MTA (B) or H1993-MTA (C) cells transfected with si-control, si-FGF2, si-TS, or si-FGF2 + TS. The error bars in each graph represent the standard error of the value obtained in the experiments performed in triplicate.