. 2019 Feb 5;10(11):1171–1192. doi: 10.18632/oncotarget.26622

Table 1. IC₅₀ for pemetrexed (MTA) in the parental and pemetrexed-resistant lung cancer cell lines.

Cell line	PC9	PC9-MTA	H1993	H1993-MTA
IC₅₀ (μM)^a (mean ± SD)	1.30 ± 0.26	> 100	0.05 ± 0.02	7.30 ± 0.03
Relative resistance ratio^b		> 77		146

^aIC₅₀: half-maximal inhibitory concentration

^bRelative resistance ratio = IC₅₀ of pemetrexed-resistant cells/IC₅₀ of parental cells

Table 1. IC50 for pemetrexed (MTA) in the parental and pemetrexed-resistant lung cancer cell lines.