TABLE 2:
Comparison of Cytokine Gene Expressions Between the Study Groups
Cytokine | Treatment-Naïve UC Patients, Cytokine Gene Expression Fold Changea | Deep Remission UC Patients, Cytokine Gene Expression Fold Changea | Treatment-Naïve UC Patients vs Controlsb | Deep Remission vs Controlsb |
---|---|---|---|---|
IL-1β | 7.88 | 1.33 | <0.001 | 0.88 |
IL-6 | 15.98 | 1.35 | <0.001 | 0.88 |
IL-12A | 3.35 | 0.79 | 0.0404 | 0.80 |
IFN | 6.53 | 0.76 | 0.001 | 0.80 |
IL-4 | 4.58 | 1.29 | 0.008 | 0.95 |
IL-5 | 4.18 | 1.15 | 0.07 | 0.98 |
IL-17A | 33.38 | 0.84 | <0.001 | 0.76 |
IL-23A | 4.26 | 0.73 | 0.001 | 0.35 |
IL-10 | 4.13 | 1.15 | <0.001 | 0.54 |
TGF- β | 1.94 | 1.17 | 0.009 | 0.82 |
aMean fold change with respect to controls.
bAdjusted P value from the 2-tailed Student t test by Dunett post hoc.