Table 1.

Day 1 and Day 3 jejunum-specific, plasma metabolites that were differentially expressed when comparing sham to TBI (combined TBI doses).

Day 1	Jejunum			Plasma
Metabolite	Sham (mean)	TBI (mean)	P value	Sham (mean)	TBI (mean)	P value	Highest Mean
His	224.12	495.73	0.0009	73.18	99.90	0.0015	TBI
Leu	1058.54	2485.90	0.0001	179.50	226.92	0.0458	TBI
Met	344.03	782.84	0.0001	62.84	80.65	0.0444	TBI
Phe	518.77	1242.32	0.0000	68.89	85.76	0.0399	TBI
Ser	1156.66	2521.26	0.0000	131.74	185.58	0.0065	TBI
Thr	751.85	1637.56	0.0000	174.13	252.75	0.0019	TBI
LPC_17–0	3.41	4.61	0.0001	2.21	2.62	0.0192	TBI
LPC_18–0	101.11	129.94	0.0003	74.33	97.46	0.0003	TBI
PC_38–5	215.70	187.03	0.0279	68.43	51.13	0.0025	Sham
PC_O-36–2	81.14	96.54	0.0325	14.14	16.37	0.0218	TBI
PC_O-38–2	64.16	98.81	0.0004	8.84	12.15	0.0000	TBI
PC_O-40–4	23.90	31.25	0.0047	3.54	4.23	0.0140	TBI
Cit / Arg	1.13	0.15	0.0004	0.61	0.41	0.0053	Sham
CPT-I ratio	0.02	0.01	0.0085	0.02	0.01	0.0147	Sham
Day 3	Jejunum			Plasma
Metabolite	Sham (mean)	TBI (mean)	P value	Sham (mean)	TBI (mean)	P value	Highest Mean
Cit	165.18	51.86	0.0000	62.98	10.13	0.0000	Sham
Gln	826.48	2136.90	0.0000	698.50	1081.30	0.0314	TBI
Kynurenine	2.99	5.18	0.0005	1.03	1.69	0.0005	TBI
LPC_17–0	3.41	4.90	0.0000	2.21	3.16	0.0009	TBI
LPC_18–0	101.11	140.67	0.0000	74.33	110.80	0.0007	TBI
LPC_18–2	56.32	44.22	0.0005	133.55	102.80	0.0175	Sham
LPC_24–0	1.09	1.45	0.0038	1.16	1.47	0.0100	TBI
PC_30–0	30.02	26.62	0.0313	1.16	0.91	0.0007	Sham
PC_36–0	8.41	11.79	0.0002	2.09	2.61	0.0015	TBI
PC_38–4	741.41	890.50	0.0037	171.13	193.69	0.0419	TBI
SM_40–2 OH	12.77	18.64	0.0013	2.60	3.33	0.0341	TBI
SM_40–3 OH	4.14	5.89	0.0005	1.88	2.35	0.0249	TBI
SM_34–2	7.61	9.26	0.0009	5.04	6.00	0.0404	TBI
SM_36–1	73.38	85.89	0.0284	2.07	3.32	0.0010	TBI
SM_36–2	5.08	6.86	0.0003	0.96	1.37	0.0017	TBI
SM_42–2	65.48	96.84	0.0001	20.32	26.43	0.0072	TBI
Cit / Arg	1.13	0.05	0.0001	0.61	0.14	0.0000	Sham
MUFA_PC / SFA_PC	2.25	2.14	0.0491	7.39	5.27	0.0000	Sham