Table 1b.

Echocardiography data from the same groups of rats 100 days after irradiation. Data are expressed as mean ± standard deviation (SD).

Echocardiogram Parameters	Mean ± SD
Days	100	100	100	100
Groups	0 Gy n=11	0 Gy + Lis n=5	13 Gy only n=8	13 Gy + lis n=9
HR (beats/min)	392±44	407±50	338±58	385±45
SV (ml)	0.49±0.11	0.51±0.10	0.40±0.10	0.33±0.12*
RV width (cm)	0.27±0.04		0.24±0.03	0.28±0.03
LVIDd (cm)&	3.37±0.39	3.54±0.23	4.12±0.79*	3.50±0.63
EDV (ml)&	3.23±0.85	3.41±0.68	3.35±1.05	2.48±1.11
IVSD (cm)&	0.77±0.09	0.80±0.17	1.12±0.20+*	1.18±0.38*
LVPWd (cm)&	0.80±0.19	0.65±0.09	1.04±0.09+*	0.99±0.20*
ESV (ml)&	0.62±0.30	0.63±0.20	0.49±0.25	0.31±0.36
LVIDs (cm)&	1.86±0.31	1.96±0.19	2.11±0.55	1.49±0.73
TAPSE	0.21±0.04		0.17±0.2	0.14±0.03*
PAT (ms)	27.05±4.22	21.34±4.57	24.95±8.05	16.53±6.72*#
ET (ms)	65.05±6.68	62.07±4.93	83.7±12,46+*	68.67±7.09#
PAT/ET	0.42±0.05	0.34±0.05	0.30±0.11	0.24±0.10*
IVRT (ms)	10.54±4.55	8.27±0.98	17.31±6.03+*	15.59±6.01
RVOT (cm)	2.52±0.43	2.64±0.36	3.73±0.51+*	2.66±0.46#
% EF	81.0±5.3	81.7±2.5	85.4±5.4	90.0±8.1*
% FS	44.8±5.3	45.2±2.6	49.6±5.4	59.1±15.2*
TR frequency	0/11	0/5	0/8	3/9

HR-heart rate, SV-stroke volume, RV width-right ventricular width, LVIDd-left ventricular internal dimension (diastole), EDV-left end diastolic volume, IVSD-inter ventricular septum diastole, LVPWd-left ventricle posterior wall (diastole), ESV-left end systolic volume, LVIDs-left ventricular internal dimension (systole), TAPSE-tricuspid annular peak systolic excursion, PAT-pulmonary acceleration time, PAT/ET- pulmonary acceleration time/ejection time, ET-ejection time, IVRT-isovolumic relaxation time, RVOT-right ventricular outflow tract, EF-ejection fraction, FS-fractional shortening, TR-tricuspid regurgitation.

^&normalized to body weight (Kg⁻¹);

^*p<0.0083 versus nonirradiated rats at 100 days;

^#p<0.0083 versus irradiation only at 100 days;

⁺p<0.0083 versus nonirradiated with lisinopril rats at 100 days.