Table 3.
Comparison of key echocardiographic parameters between 15 Gy whole thorax irradiation [WTI, (Medhora et al. 2015)] and 13 Gy leg-out partial body irradiation (PBI). Data are expressed as mean ± standard deviation (SD).
Echocardiogram Parameters | 15 Gy WTI (42 days) n=6, Mean ± SD |
13 Gy PBI (50 days) n=12, Mean ± SD |
Implication differences in the two models |
---|---|---|---|
RV width (cm) | 0.44±0.06 | 0.25±0.06* | Higher PAH in 15 Gy |
RV free wall (cm) | 0.14±0.05 | 0.10±0.05 | |
CO (ml/min) | 54.7±30.8 | 116.9±78.2 | Worse heart function in 15 Gy |
PAT (ms) | 13.0±2.14 | 18.8±6.16* | Higher PAH in 15 Gy |
PAT/ET | 0.19±0.04 | 0.28±0.10* | Higher PAH in 15 Gy |
IVRT (ms) | 39.6±7.65 | 19.6±7.75* | Worse heart function in 15 Gy |
e′ (m/s) | 0.03±0.01 | 0.05±0.02* | Higher PAH in 15 Gy |
RV-right ventricular, CO-cardiac output, PAT-pulmonary acceleration time, PAT/ET-pulmonary acceleration time/ejection time, IVRT-isovolumic relaxation time, e′-early diastolic mitral annulus velocity, PAH-pulmonary artery hypertension.
p<0.05 versus 15 Gy WTI.