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. 2018 Nov 30;6(2):132–138. doi: 10.1002/mdc3.12706

Table 1.

Baseline demographics between tetrabenazine and risperidone groups

Tetrabenazine Risperidone P‐value
N 72 72
% Female 63.6 50.0 53.1
CAG, mean ± S.D. 44.26 ± 3.24 43.79 ± 3.18 0.379
Age0 (yrs), mean ± S.D. 53.77 ± 11.55 54.01 ± 11.85 0.904
AMO (yrs), mean ± S.D. 44.42 ± 10.63 46.72 ± 10.55 0.199
CAP0, mean ± S.D. 117.60 ± 14.82 114.47 ± 17.40 0.247
TMS0, mean ± S.D. 40.81 ± 17.70 39.56 ± 17.89 0.674
TFC0, mean ± S.D. 7.10 ± 3.20 7.24 ± 3.14 0.793
Weight0 (kg), mean ± S.D. 73.03 ± 15.80 77.50 ± 17.33 0.108
BMI0 (kg/m2), mean ± S.D. 25.57 ± 4.86 26.45 ± 4.79 0.272
Baseline depression score, mean ± S.D. 1.39 ± 2.53 3.09 ± 3.94 0.003
Baseline suicidality score, mean ± S.D. 0.07 ± 0.35 0.24 ± 0.75 0.082
Baseline aggression score, mean ± S.D. 0.83 ± 1.99 1.01 ± 2.16 0.603
Baseline irritability score, mean ± S.D. 1.99 ± 2.85 2.73 ± 3.70 0.178
Time between first and second visit (yrs), mean ± S.D. 1.09 ± 0.22 1.07 ± 0.25 0.641
Daily dose (mg), mean ± S.D.1 56.53 ± 41.17 1.76 ± 1.60 N/A
Prior time on therapy (yrs), mean ± S.D. 1.80 ± 2.05 2.39 ± 2.49 0.125
Medication indicated for chorea, %1 100 55.6 N/A

Abbreviations: AMO, Age of motor onset; BMI0, Baseline body mass index; CAG, Cytosine‐Adenine‐Guanine; CAP0, Baseline disease burden score calculated (age0 x [CAG‐30]/6.27); TFC0, Baseline Total Functional Capacity score; TMS0, Baseline total motor score.

1

Statistical significance not calculated