Fig. 4. SOC channel inhibitor SKF-96365 reduced tunicamycin-induced ER stress to protect endothelial function.
HUVECs were preincubated with 1.25, 2.5, 5 µM SKF96365 before treatment with 1 µg/ml tunicamycin. BiP (A), CHOP (B), and eNOS (C) expression were determined by western blotting. *p < 0.05 vs. control; #p < 0.05 vs. tunicamycin treatment only, n = 4.