Skip to main content
. Author manuscript; available in PMC: 2019 Dec 1.
Published in final edited form as: Clin Immunol. 2018 Oct 16;197:205–218. doi: 10.1016/j.clim.2018.10.008

Figure 6. BI-BTK-1 reduces kidney inflammatory gene expression.

Figure 6.

RT-PCR was performed on NZB/W (A) and MRL/lpr kidneys (B). For both strains, BI-BTK-1 significantly reduces the expression of inflammatory mediators expressed within the kidney. (NZB/W : CC, n=13; BI-BTK-1 0.3 mg/kg, n=14; 1 mg/kg, n=15; 3 mg/kg, n=14; 10 mg/kg, n=15; PBS, n=15; CTX, n=9; NZW, n=10; young NZB/W, n=10) (MRL/lpr mice: CC, n=9; BI-BTK-1 10 mg/kg, n=12) (*p<0.05, **p<0.01, ***p<0.001, ****p<0.0001).