Table 3.

Association of biomarkers at inclusion and lowest/highest measurement with clinical parameters.

		Aphasia	Motor deficit	Dysarthria	Dysphagia	Sex	NIHSS	mRS d90	Age
HLA-DR	Inclusion	0.405	0.979	0.548	0.757	0.606	0.409	0.052	0.249
	Lowest	0.987	0.436	0.959	0.173	0.340	0.099	0.030	0.069
IL-6	Inclusion	0.410	0.478	0.912	0.739	0.824	0.005	0.252	0.001
	Highest	0.369	0.281	0.983	0.438	0.884	0.005	0.015	0.030
IL-8	Inclusion	0.443	0.050	0.640	0.552	0.803	0.073	0.226	0.339
	Highest	0.633	0.393	0.386	0.467	0.597	0.331	0.683	0.566
IL-10	Inclusion	0.416	0.468	0.136	0.611	0.564	0.916	0.248	0.460
	Highest	0.247	0.360	0.257	0.727	0.989	0.683	0.587	0.236
LBP	Inclusion	0.086	0.364	0.958	0.660	0.227	0.291	0.952	0.148
	Highest	0.857	0.861	0.442	0.353	0.621	0.062	0.637	0.152
MPproANP	Inclusion	0.486	0.640	0.012	0.029	0.914	0.163	0.654	0.005
	Highest	0.521	0.287	0.047	0.005	0.926	0.068	0.911	0.005
MPproADM	Inclusion	0.001	0.320	0.310	0.915	0.296	0.241	0.264	< 0.001
	Highest	0.351	0.209	0.618	0.979	0.547	0.158	0.043	0.001
CTproET	Inclusion	0.398	0.323	0.613	0.994	0.962	0.160	0.344	0.018
	Highest	0.015	0.330	0.893	0.888	0.933	0.092	0.169	0.039
Copeptin us	Inclusion	0.720	0.455	0.548	0.436	0.357	0.768	0.006	0.540
	Highest	0.335	0.910	0.354	0.441	0.115	0.918	0.144	0.298
PCT us	Inclusion	0.643	0.381	0.007	0.736	0.286	0.254	0.962	0.975
	Highest	0.855	0.560	0.056	0.908	0.362	0.634	0.230	0.711

Values given are two-sided p-values obtained by a students' t-test; Bold text denotes significant associations; HLA-DR, Human leukocyte antigen expression on monocytes; IL-6, IL-8, IL-10, three interleukins; LBP, lipopolysaccharide-binding protein; MRproANP, mid-regional pro atrial natriuretic peptide; MRproADM, mid-regional pro adrenomedullin; CTproET, C-terminal pro endothelin; CPus, ultrasensitive copeptin; PCTus, ultrasensitive procalcitonin.