Table 4.

Association of biomarkers at inclusion and lowest/highest measurement with imaging parameters.

		Initial DWI volume	Initial PI deficit	Initial mismatch	Final FLAIR volume
HLA-DR	At Inclusion	0.933	0.936	0.716	0.397
	Lowest	0.678	0.234	0.443	0.300
IL-6	At Inclusion	0.002	0.016	0.030	0.006
	Highest	0.009	0.029	0.042	0.383
IL-8	At Inclusion	0.955	0.667	0.928	0.068
	Highest	0.787	0.798	0.099	0.347
IL-10	At Inclusion	0.290	0.555	0.701	0.822
	Highest	0.081	0.101	0.595	0.435
LBP	At Inclusion	0.084	0.877	0.625	0.546
	Highest	0.037	0.349	0.431	0.688
MPproANP	At Inclusion	0.949	0.945	0.566	0.830
	Highest	0.853	0.795	0.486	0.941
MPproADM	At Inclusion	0.882	0.901	0.123	0.130
	Highest	0.682	0.801	0.267	0.340
CTproET	At Inclusion	0.923	0.887	0.665	0.827
	Highest	0.834	0.906	0.541	0.849
Copeptin us	At Inclusion	0.144	0.801	0.457	0.701
	Highest	0.487	0.673	0.648	0.815
PCT us	At Inclusion	0.804	0.214	0.224	0.637
	Highest	0.418	0.151	0.381	0.513

Values given are two-sided p-values obtained by a Spearman's correlation; Bold text denotes significant associations; HLA-DR, Human leukocyte antigen expression on monocytes; IL-6, IL-8, IL-10, three interleukins; LBP, lipopolysaccharide-binding protein; MRproANP, mid-regional pro atrial natriuretic peptide; MRproADM, mid-regional pro adrenomedullin; CTproET, C-terminal pro endothelin; CPus, ultrasensitive copeptin; PCTus, ultrasensitive procalcitonin.