Figure 2.

Glycolysis, gluconeogenesis, the fragmented TCA cycle, anaplerotic reactions and global regulators involved in metabolism. Schematic overview of the glycolysis, gluconeogenesis, the fragmented TCA cycle showing the oxidative and the reductive pathway, including anaplerotic reactions as well as global regulators controlling the central metabolism. Global regulators are marked by colored dots, ATP producing and reducing equivalent consuming/producing reactions are marked by colored arrows. (BP: bisphosphate, P: phosphate, Ac: Acetyl, -OH: -hydroxy). Dashed arrows represent multiple reactions.