Table 1.
Comparison of demographic variables between the groups from our cohort and the ADNI cohort.
| Primary cohort |
Validation cohort |
t-Test/χ2 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| AD |
MCI |
NC |
ANOVA |
AD |
MCI |
NC |
ANOVA |
AD |
MCI |
NC |
|
| (n = 25) | (n = 29) | (n = 34) | p | (n = 27) | (n = 21) | (n = 22) | p | p | p | p | |
| Age(year) | 73.48 ± 11.83 | 74.07 ± 10.76 | 69.03 ± 11.53 | 0.163 | 76.00 ± 9.78 | 72.52 ± 8.71 | 73.27 ± 6.05 | 0.321 | 0.405 | 0.591 | 0.118 |
| Sex, n(%) | |||||||||||
| Female | 12(48%) | 13(44.8%) | 11(32.4%) | 0.420 | 15(55.5%) | 10(47.6%) | 6(27.3%) | 0.256 | 0.782 | 0.536 | 0.461 |
| Male | 13(52%) | 16(55.2%) | 23(67.6%) | 12(44.5%) | 11(52.4%) | 16(72.7%) | |||||
| Education (year) | 11.64 ± 2.72 | 12.83 ± 2.62 | 12.91 ± 2.24 | 0.121 | 14.96 ± 2.79 | 15.00 ± 2.75 | 15.41 ± 2.59 | 0.828 | <0.001* | 0.007 | 0.001 |
| MMSE score | 16.44 ± 5.98 | 25.55 ± 2.25 | 29.06 ± 1.20 | <0.001* | 22.07 ± 2.63 | 27.24 ± 1.55 | 29.50 ± 0.60 | <0.001* | <0.001* | 0.005 | 0.117 |
| MoCA score | 11.48 ± 4.14 | 21.72 ± 2.56 | 27.12 ± 1.97 | <0.001* | 14.85 ± 4.10 | 22.62 ± 2.16 | 28.23 ± 1.31 | <0.001* | 0.002 | 0.218 | 0.047 |
Note: Data are presented as means ± standard deviations. Primary cohort means our cohort; Validation cohort means the ADNI cohort; AD, Alzheimer's disease; MCI, mild cognitive impairment; NC, normal control; MMSE, Mini–Mental State Examination (MMSE); MoCA, Montreal Cognitive Assessment; t-test/χ2 means the statistics in the demographic variables comparisons between primary cohort and the ADNI cohort; * denotes a significant difference with a p value <.05.