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. 2019 Feb 18;22:101723. doi: 10.1016/j.nicl.2019.101723

Table 5.

Summary of change in mean FA, mean MD, location of points with significant difference in pointwise comparison of tract profiles across 20 fiber tracts among the groups from our cohort.

Changes in mean FA
Location of changes in FA
Changes in mean MD
Location of changes in MD
AD vs NC MCI vs NC AD vs MCI AD vs NC MCI vs NC AD vs MCI AD vs NC MCI vs NC AD vs MCI AD vs NC MCI vs NC AD vs MCI
ATR_L + A/M
ATR_R
CST_L + S/M
CST_R + S
CCing_L +
CCing_R + P/M M + P
CHippo_L + P
CHippo_R +
CC Splenium L
CC Genu R
IFOF_L + + P/M P
IFOF_R + + P/M
ILF_L P + A/M
ILF_R M + A
SLF_L + A/P
SLF_R
UF_L + F + M/F
UF_R + + W M
AF_L + T/M T
AF_R

Note: AD, Alzheimer's disease; MCI, mild cognitive impairment; NC, normal control; ATR, anterior thalamic; CST, corticospinal tract; CCing, cingulum cingulate; CHippo, cingulum hippocampus; CC, corpus callosum; IFOF, inferior fronto-occipital fasciculus; ILF, inferior longitudinal fasciculus; SLF, superior longitudinal fasciculus; UF, uncinated fasciculus; AF, arcuate fasciculus. L, left; R, right. +, difference between the groups; −, no difference between the groups; A, difference in anterior part of the fiber; P, difference in posterior part of the fiber; S, difference in superior part of the fiber; M, difference in middle part of the fiber; T, difference in the temporal lobe part of the fiber; W, difference in the entire fiber. FDR correction was used in comparison in mean FA with a p value<.05. FWE correction was used in point wised location changes with a p value<.05.