Table 7.
Summary of change in the location of points with significant difference in pointwise comparison of tract profiles across 20 fiber tracts among the groups from the ADNI cohort.
| Location of changes in FA |
Location of changes in MD |
|||||
|---|---|---|---|---|---|---|
| AD vs NC | MCI vs NC | AD vs MCI | AD vs NC | MCI vs NC | AD vs MCI | |
| ATR_L | – | – | – | A | – | – |
| ATR_R | – | – | – | A | – | – |
| CST_L | – | – | – | – | – | – |
| CST_R | – | – | – | – | – | – |
| CCing_L | – | – | – | – | – | – |
| CCing_R | – | – | – | M | – | – |
| CHippo_L | – | – | – | A | – | M |
| CHippo_R | – | – | – | – | – | – |
| CC Splenium | – | – | – | R | – | – |
| CC Genu | R | – | – | – | – | – |
| IFOF_L | – | – | – | M | – | – |
| IFOF_R | – | – | – | M | – | – |
| ILF_L | – | – | A/M/P | – | M/P | |
| ILF_R | – | – | – | M/P | – | – |
| SLF_L | – | – | – | M/P | – | – |
| SLF_R | – | – | – | M/P | – | – |
| UF_L | F | – | F | F/M/T | – | M |
| UF_R | – | – | F | – | – | – |
| AF_L | – | – | – | M/F | – | – |
| AF_R | – | – | – | – | – | – |
Note: AD, Alzheimer's disease; MCI, mild cognitive impairment; NC, normal control; ATR, anterior thalamic; CST, corticospinal tract; CCing, cingulum cingulate; CHippo, cingulum hippocampus; CC, corpus callosum; IFOF, inferior fronto-occipital fasciculus; ILF, inferior longitudinal fasciculus; SLF, superior longitudinal fasciculus; UF, uncinated fasciculus; AF, arcuate fasciculus. R, right; A, difference in anterior part of the fiber; P, difference in posterior part of the fiber; M, difference in middle part of the fiber; T, difference in the temporal lobe part of the fiber; F, difference in the frontal lobe part of the fiber. FDR correction was used in comparison in mean FA with a p value<.05. FWE correction was used in point wised location changes with a p value<.05.