. 2018 Oct 1;47(1):215–224. doi: 10.1177/0300060518799869

Table 4.

Correlations between clinical TNM stage and D-dimer and fibrinogen levels.

Clinical stage			P value
T stage	T1+T2+T3	T4
D-dimer (mean ± SD)Median (min, max)	1.14 ± 1.16	1.37 ± 1.38	0.183^$
D-dimer (mean ± SD)Median (min, max)	0.62 (0.12, 5.27)	0.91 (0.25, 5.27)	0.183^$
>0.55 mg/L (n, %)	23, 53.5%	30, 76.9%	0.027
Fibrinogen (mean ± SD) Median (min, max)	378.35 ± 113.72	391.34 ± 106.37	0.504^$
Fibrinogen (mean ± SD) Median (min, max)	384 (236.0, 783.0)	397 (203.0, 666.0)	0.504^$
>Normal	20, 46.5%	18, 46.2%	0.974
N stage	N0+N1+N2	N3
D-dimer (mean ± SD)Median (min, max)	0.83 ± 0.96	1.77 ± 1.41	<0.001^$
D-dimer (mean ± SD)Median (min, max)	0.50 (0.12, 5.27)	1.20 (0.28, 5.27)	<0.001^$
>0.55 mg/L (n, %)	18, 40.0%	35, 94.6%	<0.001
Fibrinogen (mean ± SD)Median (min, max)	386.18 ± 112.83	382.52 ± 107.51	0.915^$
Fibrinogen (mean ± SD)Median (min, max)	397.0 (203.0, 783.0)	379.0 (236.0, 666.0)	0.915^$
>Normal	21, 46.7%	17, 46.0%	0.948
TNM stage	I+II+IIIa	IIIb+IV
D-dimer (mean ± SD)Median (min, max)	0.57 ± 0.57	1.46 ± 1.35	<0.001^$
D-dimer (mean ± SD)Median (min, max)	0.42 (0.15, 2.81)	0.91 (0.12, 5.27)	<0.001^$
>0.55 mg/L (n, %)	1, 5.4%	52, 82.5%	<0.001
Fibrinogen (mean ± SD)Median (min, max)	371.02 ± 103.67	388.60 ± 112.06	0.370^$
Fibrinogen (mean ± SD)Median (min, max)	358.0 (253.0, 623.0)	397 (203.0, 783.0)	0.370^$
>Normal	8, 42.1%	30, 47.6%	0.673

SD, standard deviation. ^$, Mann–Whitney test