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. 2019 Jan 30;24(3):502. doi: 10.3390/molecules24030502

Table 4.

IC50 values of cytotoxic activity against MDA-MB-468, MCF-7 and PBMCs and % of viability on PBMCs at different concentrations of the extract and CisP. Cells were treated with methanolic extracts of needles and berries from Juniperus oxycedrus subsp. oxycedrus.

Sample Tested IC50 of Cytotoxic Activity Against Tumor Cells % of Viability in PBMCs
MDA-MB-468 MCF-7 PBMCs Concentration (µg/mL)
12.5 3.125 0.78125
Joo N 14.30 ± 3.3 a 10.10 ± 1.40 a >50 a 91.34 ± 7.72 a 110.40 ± 9.51 a 126.82 ± 10.70 a
Joo B 6.40 ± 1.1 b 5.20 ± 2.00 b 49 a 60.40 ± 7.68 a 106.30 ± 1.89 a 118.59 ± 5.56 a
CisP 0.20 ± 0.0 c 2.20 ± 0.40 c 0.27 b 16.08 ± 3.39 b 30.08 ± 3.58 b 37.96 ± 3.44 b

Each value represents the mean ± standard deviation of three independents replicates. Different letters in the same column indicate significant differences (p < 0.05) within conditions according to two-way ANOVA multiple comparison range Test.