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HeLa705 cells in complete growth medium were incubated for 16 h with various concentrations of conjugated or unconjugated oligonucleotide. Thereafter the cells were recovered and assayed for luciferase activity. In one case cells were post-treated with 10 μM UNC7938 for 4 h after exposure to SSO623 and then assayed. RLU = relative luminescence units; n = 3. Means and standard errors shown. SSO623: r5’GTTATTCTTTAGAATGGTGC3’, all 2’-O-Me and phosphorothioate (PS) (T = ribothymidine).
