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. 2019 Feb 12;24(3):645. doi: 10.3390/molecules24030645

Table 1.

DNA Repair proteins employed in ligand-receptor docking [39].

Cancer DNA Repair Proteins Whose Downregulation is Associated with Prolonged OS
AML RAD23A, EME2, APEX2
Breast ATRIP, FANCC, RAD1, RFC3, NEIL3, EXO1, FANCB, FANCD2, FANCI, RAD51, XRCC4
Colon RAD23A, RFC2, POLL, MLH3, FANCL
GBM XRCC5, NBN, DDB1, GTF2H2, ERCC4, ALKBH2, APEX1, PRKDC, PMS1, REV1
Renal papillary BLM, RAD1, FEN1, LIG1, EXO1, MSH6, BRCA2, EME1, FANCB, LIG4
Lung BRCA1, NBN, RAD1, NEIL3, MMS19, FANCI, XRCC1, XRCC5
Melanoma MDC1, NBN, MUTYH, POLE, UNG, FANCE, FANCI, POLI, POLK
Ovarian PARP2, GTF2H4, SMUG1, DCLRE1B, GPS1, FANCL, APEX2, PMS1, XRCC6, MSH6, UNG, RAD51, RAD23A, EXO1, MUS81