Skip to main content
. 2019 Jan 24;24(3):426. doi: 10.3390/molecules24030426

Table 3.

Structures of NDIs used to target gene expression.

Name R X Y Targeted Gene(s) Ref.
11 graphic file with name molecules-24-00426-i051.jpg graphic file with name molecules-24-00426-i052.jpg graphic file with name molecules-24-00426-i052.jpg hTel, KIT, BCL-2 [76,87]
25 graphic file with name molecules-24-00426-i053.jpg graphic file with name molecules-24-00426-i054.jpg graphic file with name molecules-24-00426-i054.jpg KIT, HIF1α [77]
55 graphic file with name molecules-24-00426-i055.jpg -H -H KIT2 [79]
28 graphic file with name molecules-24-00426-i056.jpg graphic file with name molecules-24-00426-i057.jpg graphic file with name molecules-24-00426-i057.jpg BCL-2, KRAS [86]
56 graphic file with name molecules-24-00426-i058.jpg graphic file with name molecules-24-00426-i059.jpg -H TERT, BCL-2 [89]
37 graphic file with name molecules-24-00426-i058.jpg graphic file with name molecules-24-00426-i060.jpg -H TERT, BCL-2, RET, multi-targeting [89,92]
57 graphic file with name molecules-24-00426-i058.jpg graphic file with name molecules-24-00426-i060.jpg graphic file with name molecules-24-00426-i060.jpg TERT, BCL-2 [89]
60 graphic file with name molecules-24-00426-i056.jpg -H graphic file with name molecules-24-00426-i052.jpg Multi-targeting [95]
58 graphic file with name molecules-24-00426-i062.jpg graphic file with name molecules-24-00426-i054.jpg graphic file with name molecules-24-00426-i054.jpg AR [93]
61 graphic file with name molecules-24-00426-i053.jpg graphic file with name molecules-24-00426-i061.jpg graphic file with name molecules-24-00426-i061.jpg hTel, HSP90 [98]
Name Structure X Targeted Gene(s) Ref.
51 graphic file with name molecules-24-00426-i050.jpg -NH- hTel, KIT2 [78]
52 -NH(CH2)2NH-
53 -NH(CH2)3NH-
54 -NH(CH2)4NH-
Name Structure Targeted Gene(s) Ref.
59 graphic file with name molecules-24-00426-i046.jpg AR [94]