Table 1.
Clinical examinations and outcomes
| Patient number | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 |
|---|---|---|---|---|---|---|---|---|
| Age (years) | 42 | 45 | 30 | 50 | 52 | 59 | 55 | 54 |
| BMI (kg/m2) | 29.9 | 25.5 | 27.0 | 24.0 | 20.7 | 30.6 | 22.7 | 21.2 |
| Duration of symptoms (years) | 20 | 15 | 8 | 5 | 9 | 12 | 15 | 10 |
| Type of OA | PT | PT | PT | Gen | Gen | Gen | Gen | Gen |
| Location of defect | LFC | LFC, PF | MFC | MFC | MFC | MFC | MFC | MFC, PF |
| Size of defect (cm2) | 3.38 | 2.25 3.20 |
3.92 | 4.10 | 3.98 | 3.12 | 4.02 | 3.57 2.88 |
| Outerbridge classification | 3 | 3 | 3 | 4 | 4 | 4 | 4 | 4 |
| KL grade | 2 | 2 | 2 | 3 | 4 | 3 | 3 | 3 |
| Surgical treatments | ACLR | ACLR | ACLR | OWHTO | OWHTO | OWHTO | OWHTO | OWHTO |
| Thickness of RC (mm) | 3.5 | LFC 2.4 PF 4.2 |
3.1 | 3.2 | 3.6 | 3.4 | 2.4 | MFC 2.1 PF 2.9 |
| Viscoelasticity of RC by LIPA (preop. value) | 0.87 (0.65) | LFC 1.04 (0.74) PF 1.06 (0.60) |
0.98 (0.78) | 0.87 (0.52) | 0.89 (0.70) | 0.90 (0.60) | 0.88 (0.69) | MFC 0.92 (0.58) PF 0.88 (ND) |
| OARSI histological score | 4 | 9 | 2 | 12 | 3 | 3 | 5 | 14 |
| Mankin score | 3 | 7 | 4 | 8 | 3 | 4 | 3 | 6 |
| Histological appearance | HL | HL | HL | HL | HL | HL | HL | HL |
| Last follow-up date (months) | 61 | 49 | 36 | 47 | 36 | 36 | 36 | 36 |
BMI body mass index, OA osteoarthritis, PT post-traumatic, Gen general, LFC lateral femoral condyle, PF patellofemoral groove, MFC medial femoral condyle, KL grade Kellgren–Lawrence grade, ACLR anterior cruciate ligament reconstruction, OWHTO open-wedge high tibial osteotomy, RC regenerated cartilage, LIPA laser-induced photoacoustic measurement, ND not detectable, OARSI Osteoarthritis Research Society International, HL hyaline-like cartilage