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. 2019 Feb 22;9:2573. doi: 10.1038/s41598-019-39119-z

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Cochlear morphology and spiral ganglion cell (SGC) density are normal in K_Na1 DKO mice. Cochlear morphology and SGC density were examined in mid-modiolar serial sections through the cochlea isolated from 6-week-old WT and DKO mice. (A) No differences between genotypes were seen in structures of the inner ear, including hair cells, SGCs, stria vascularis, spiral ligament and all supporting structures of the cochlear duct. (B) Spiral ganglion cell-density was not significantly different between WT (black) and DKO (grey) mice in either cochlear apical or basal turns. Data are plotted to show individual replicates (animals) and mean ± SEM. Values (mean ± SEM) and statistical analyses are provided in the Results.