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. 2019 Feb 21;9:2526. doi: 10.1038/s41598-019-38920-0

Table 1.

List of the 43 VOCs that have a p-value less than 0.1 via the Student’s T-test or Wilcoxon’s Rank sum test when classifying mice with no cancer and mice that have breast cancer.

Name Abbrev. RT (min) T test p-value Rank-sum p-value Regulation CAS #
5-Octen-1-ol, (Z)-* 5-OCT 8.6 2.3E-4 1.4E-4 down 64275-73-6
Benzene, 4-ethenyl- 1,2-dimethyl-* BNZE 10.45 4.5E-4 6.3E-4 down 27831-13-6
Bicyclo[3.1.0] hexan-2-one, 3,3,6-trimethyl-* BCY3 8.87 0.003 7.6E-4 down 53966-40-8
Bicyclo[2.2.1]heptane, 7,7-dimethyl-2-methylene* BCY2 8.52 0.006 0.006 down 471-84-1
Pinocarvone* PINC 11.66 0.017 0.002 down 30460-92-5
Benzyl methyl disulfide* BMDS 15.07 0.076 0.052 down 699-10-5
Benzene, 1-ethyl-4-methoxy-ǂ BETH 11.07 3.2E-4 0.002 down 1515-95-3
Amantadine AMAN 12.61 0.001 0.008 down 768-94-5
Benzene, 1-(1,5-dimethyl-4-hexenyl)-4-methyl- BEHX 16.45 0.002 0.019 down 644-30-4
Bergamotene BERG 16.56 0.002 0.002 down 17699-05-7
1,3,5-Undecatriene ǂ UNDE 11.9 0.002 3.7E-4 down 51447-08-6
Benzeneacetaldehyde ǂ BNAT 9.61 0.006 9.4E-4 down 122-78-1
Sorbic acid vinyl ester SORB 8.56 0.008 8.8E-4 down 42739-26-4
4(1 H)-Pyridone 4-PYR 8.43 0.010 0.019 up 108-96-3
(E)-α-Bisabolene CYCL 17.29 0.011 0.008 down 17627-44-0
Farnesene FRNS 16.76 0.013 0.026 up 502-61-4
Ethanone, 1-(1H-pyrrol-2-yl)- ETHP 9.93 0.015 0.013 down 1072-83-9
Himachalol HIMA 19.23 0.017 0.024 down 1891-45-8
2-Hexanone 2-HXO 4.43 0.017 0.009 down 591-78-6
Ethanone, 2-cyclohexyl-1-(1-methyl-1H-imidazol-4-yl)- ETCH 19.51 0.019 0.003 down 69393-35-7
(Z)-γ-Bisabolene 1-MCY 16.94 0.021 0.005 down 495-62-5
1-(4-butoxy-2-methylphenyl)ethanone 4-BUT 19.42 0.021 0.004 down NA
Benzenemethanol, 4-trimethyl- BEME 11.97 0.022 0.014 down 1197-01-9
Benzaldehyde, 4-ethyl- BENE 11.88 0.029 0.125 down 4748-78-1
Bisobolol BIBO 19.22 0.034 0.072 down 515-69-5
Benzene, n-butyl- BZNB 8.81 0.038 0.021 down 104-51-8
Benzene, [(methylsulfonyl)methyl]- BNMS 15.08 0.045 0.026 down 3112-90-1
Benzene, 1,3-diethyl-5-methyl- BNDI 12.75 0.050 0.050 up 2050-24-0
Formamide, N-phenyl- FORM 12.54 0.051 0.022 down 103-70-8
Benzaldehyde BNZA 7.88 0.063 0.018 up 100-52-7
2-Propanamine, 2-methyl 2-PRO 2.55 0.069 0.582 down 75-64-9
Cyclohexanol, 2,6-dimethyl- CHXO 9.99 0.069 0.302 down 5337-72-4
1,4-Pentadiene 1-PEN 1.62 0.081 0.018 down 591-93-5
D-Limonene DLIM 9.32 0.084 0.066 down 5989-27-5
Phenol, 2,4-dichloro- PHEN 11.7 0.092 0.108 down 120-83-2
2-Pentanone, 3-methyl- 2-PTM 3.78 0.097 0.070 down 565-61-7
Thiophene, 2-pentyl- THIO 11.59 0.139 0.061 up 4861-58-9
Benzene, 1-isothiocyanato-2-methyl- BISO 13.73 0.156 0.029 up 614-69-7
Hexadecane HXDC 19.31 0.158 0.056 down 544-76-3
Benzene, 1-ethenyl-4-ethyl BNET 10.39 0.173 0.029 down 3454-07-7
β-Irone 3-BUT 19.05 0.210 0.094 down 79-70-9
Terpineol TERP 12.07 0.226 0.043 down 98-55-5
(+)-α-himachalene 1-BEN 16.82 0.259 0.042 down 3853-83-6

Features bolded are also found in Table 2, VOCs that have an asterisk (*) were utilized for two class LDA, and VOCs with a cross (ǂ) were utilized for three class LDA. All VOCs in the table were utilized to discriminate between cancer/no cancer via PCA.