Table 4.

Hazard ratios and goodness of fit of multivariate negative binomial models for predicting intradialytic hypotension.

	Model 1	Model 2	Model 3	Model 4	Model 5	Model 6
with DM	1.90	1.14	1.17	1.15	1.49	1.16
with CAD	0.75	1.01	0.98	0.98	1.09	1.00
with CHF	1.79	2.07	2.16	2.09	1.71	2.16
Age, /10 year	1.34	1.19	1.19	1.19	1.19	1.18
UFR, /kg	1.67c	1.66c	1.68c	1.68c	1.65c	1.66c
iPTH, /100 pg/mL	0.81	0.85	0.85	0.85	0.85	0.85
ARB or ACEI	0.52	0.40	0.39	0.39	0.46	0.40
CCB	0.55	0.71	0.73	0.73	0.66	0.70
β-blocker	1.27	1.10	1.07	1.08	1.04	1.09
ΔHR			1.04	1.04
ΔRRI, /0.1 msec		0.65			0.57	0.65
ΔSDNN
ΔRMSSD
ΔVLF, /100 msec2
ΔLF, /100 msec2			0.96			0.96
ΔHF, /100 msec2		0.87	0.84	0.84	0.59	0.86
ΔTP, /100 msec2		0.89c	0.90	0.89c	0.94	0.90
ΔLF/HF ratio
AIC	208.8	200.9	202.9	200.9	203.9	202.9
BIC	231.5	230.4	234.6	230.3	233.3	234.6
AUC	0.726b	0.804a	0.804a	0.802a	0.801a	0.801a
P value	0.002	<0.001	<0.001	<0.001	<0.001	<0.001

Abbreviation: DM, diabetes mellitus; CAD, coronary artery disease; CHF, congestive heart failure; UFR, ultrafiltration rate; iPTH, intact parathyroid hormone; ARB, angiotensin II receptor blocker; ACEI, angiotensin-converting-enzyme inhibitor; CCB, calcium channel blocker; HR, heart rate; RRI, R-R interval; SDNN, the standard deviation of N-N interval; RMSSD, the square root of the mean squared differences of successive NN intervals; VLF, very low frequency; LF, low frequency; HF, high frequency; TP, total power; AIC, the Akaike Information Criterion; BIC, the Bayesian Information criterion; AUC, the area-under curve.

Δ represents changes between the early and the middle phase.

Model 1, basic model in which the prior history of DM, CAD, and CHF, age, UFR, iPTH, and the history of antihypertensive agents were incorporated.

^aHazard ratio with P < 0.001.

^bHazard ratio with P < 0.01.

^cHazard ratio with P < 0.05.