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. 2019 Feb 21;10:890. doi: 10.1038/s41467-019-08719-8

Table 1.

Up- and downregulated genes in 14-day-starved cells

Gene Function Fold upregulation 14 days/exp Fold upregulation 14 days/stat
abnA Arabinan degradation 3.1 2.6
acoA, acoB, acoC Acetoin utilization 8.5, 4.8, 2.0 12.7, 3.4, 2.3
araB, araD, araL, araN, araP, araQ Arabinose utilization 2.3, 2.6, 2.4, 2.1, 3.6, 3.6 2.2, 2.0, 2.2, 2.3, 2.1, 2.5
araE Uptake of arabinose, galactose, and xylose 2.1 2.0
cwlT Conjugative transfer of ICEBs1 2.5 2.2
czcD Cation efflux, resistance against Zn, Cu, Co, Ni 2.6 2.7
exuT Hexuronate uptake 2.1 3.1
ganB Galactan utilization 2.9 3.4
hutH Histidine utilization 2.4 2.2
manA Mannose utilization 2.7 2.2
mmgB Mother cell metabolism 32.5 4.4
nicK Conjugation of ICE BS1 4.7 3.9
rbsC, rbsD Ribose uptake 3.5, 3.1 2.1, 2.3
rhiF Uptake of rhamnose oligosaccharides 2.5 4.3
sigV Resistance to lytic enzymes 2.8 3.6
uxaC, uxuA Hexuronate utilization 2.5, 2.0 3.0, 2.1
ydfQ Unknown 2.2 3.5
ydfR Unknown 19.7 2.7
ydzR Unknown 4.3 3.6
yezD Unknown 3.4 4.1
yisJ Unknown 17.2 3.0
Fold downregulation 14 days/exp Fold downregulation 14 days/stat
bioI Biosynthesis of biotin −2.3 −2.1
comC Genetic competence −2.4 −3.0
comGC, comGD, comGE, comGF, comGG Genetic competence −3.1, −3.3, −2.8, −3.1, −3.4 −3.5, −3.5, −2.9, −3.0, −2.4
coxA Resistance of the spore −2.7 −2.1
epsD, epsI, epsJ, epsL Biofilm formation −4.6, −8.1, −4.6, 8.4 −2.8, −4.5, −3.1, −5.0
nadA, nadC NAD biosynthesis −2.1, −2.4 −2.0, −2.3
rtpA Regulation of tryptophan biosynthesis −4.2 −2.6
tasA Biofilm formation −5.1 −2.7
thiS Biosynthesis of thiamine −3.5 −3.5
thiU Thiamine uptake −2.2 −2.2
yckD Unknown −3.9 −2.4
ywcJ Unknown −2.0 −2.3
ywpE Unknown −23.6 −8.3

The transcriptome profile of 14-day-starved cells was compared to those of exponential phase and stationary phase cells. Genes that showed at least a twofold up- or downregulation in both situations, with p-values lower than 0.05, are listed. Genes in an operon have been grouped together