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. 2019 Feb 22;9:2615. doi: 10.1038/s41598-019-39273-4

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Correlation between the 6-gene signature and overall survival of patients. (a) The distribution of risk scores. (b) The expression heatmap of the 6 prognostic genes. (c) Scatterplot of patient survival status. (d) Kaplan-Meier curves of overall survival of the low- and high-risk groups. (e) ROC curve for 1-year survival prediction by the 6-gene signature. (f) ROC curve for 2-year survival prediction by the 6-gene signature. The black dotted line in a and c represents the median risk score cutoff dividing patients into the low- and high-risk groups.