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. 2019 Feb 22;9:2613. doi: 10.1038/s41598-019-39036-1

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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(A) Average tumor volume is plotted relative to the number of days after treatment. Tumor volume was measured daily. The error bars represent the standard deviations of 5 mice per group. *p < 0.001 and **p < 0.76 (unpaired t test). (B) The body weight of 4T1 tumor-bearing mice was monitored after treatment.