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. 2019 Feb 21;7:52. doi: 10.1186/s40425-019-0528-x

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Clinical response to nivolumab and ipilimumab. a, Lung lesion before the treatment with anti-CTLA-4 and anti-PD-1 antibodies and after 8 weeks. There was a marked regression with 8 weeks of the treatement. b, After 16 weeks of treatment, a complete metabolic response was observed in the ¹⁸FDG-PET/CT scan