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. 2019 Feb 21;19:50. doi: 10.1186/s12906-019-2458-z

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — The protective effect of DS, SQ and DS-SQ (6:4) on EA.hy926 cells against Hcy-Ado-TNF cytotoxicity was determined by MTT assay. Cell viability, as determined for DS (a), SQ (b) and DS-SQ 6:4 (c) following treatments with Hcy-Ado-TNF in EA.hy926 cells, respectively. Cell viability was expressed as a percentage compared to control. Data shown are mean ± SEM, n > 3. * P < 0.05, ** P < 0.01, *** P < 0.001 in comparison with other combinations in the respective cell lines. d CI values were plotted as a function of fractional of cell viability (Fa) by ‘CompuSyn’ software. Fa values correspond to percentage cell viability relative to control. The solid line is the reference line, where CI value equals 1; solid line represents CI values at different Fa