Fig. 7.

RXR selective inhibitor UVI3003 reversed the anti-neuroinflammation effects of bexarotene and its regulation on downstream signaling proteins of PPARγ/SIRT6/p-FoxO3a at 24 h after SAH. a Representative western blot bands. b–h Quantitative analyses of RXR, PPARγ, SIRT6, p-FoxO3a, IL-1β, IL-6, and TNF-α in the left hemisphere at 24 h after SAH. **P < 0.01 vs. sham, ##P < 0.01 vs. SAH + vehicle, and &&P < 0.01 vs. SAH + BEXA + vehicle. Error bars were represented as mean ± SD. n = 6 per group. Bexa bexarotene